Biologics—A Treatment Option for Rheumatoid Arthritis (RA)

SIMPONI^® is a type of medicine called a biologic made from proteins found in the body.

When treating RA, SIMPONI^® is taken with another medicine called methotrexate, as directed. Studies have found that when methotrexate is taken with some biologic treatments, like SIMPONI^®, the 2 medicines together may help to control the symptoms of RA.

Biologics may help relieve the joint pain, stiffness, and swelling caused by moderate to severe RA. They are prescribed for people whose symptoms have not fully responded to other types of treatments. These medicines may include:

• NSAIDs, or nonsteroidal anti-inflammatory drugs
• DMARDs, or disease-modifying antirheumatic drugs